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CVS Caremark's decision to prefer Wegovy over Zepbound was driven by favorable rebate agreements with Novo Nordisk

Eventually, it led to the diagnosis of a rare condition called Nonarteritic Anterior Ischemic Optic Neuropathy, also known as NAION, which causes sudden, irreversible blindness, when blood flow to the optic nerve is blocked

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The percentage of patients who discontinued due to ineffective therapy was 3.6% in the liraglutide injection 1.8 mg treatment group, 6.0% in the liraglutide injection 1.2 mg treatment group, and 10.1% in the glimepiride-treatment group

The 0.25 mg starting dose follows the same elimination pattern as higher maintenance doses