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12.2 Pharmacodynamics Onset of Action The pharmacodynamic profiles for TOUJEO given subcutaneously as a single dose of 0.4, 0.6, or 0.9 U/kg in a euglycemic clamp study in patients with type 1 diabetes showed that on average, the onset of action develops over 6 hours post dose for all three single doses of TOUJEO

doi: 10.1016/j.juro.2009.11.022 [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Poore W, Boyd CJ, Singh NP, Wood K, Gower B, Assimos DG