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The following important adverse reactions are described below and elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

Palacios-OrtegaSVarela-GuruceagaMMartnezJAdeMiguel CMilagroFI

Eligible subjects were randomised 3:3:3:1:1:1 to semaglutide 0.1 mg ( N = 80), 0.2 mg ( N = 78), or 0.4 mg ( N = 82) once-daily subcutaneously or placebo ( N = 80) for 72 weeks