glp 1 super bowl commercial Serena Williams is facing heavy criticism after appearing in a LX promoting a GLP-1 weight-loss medication. Critics took to social media saying it was “wrong” or even “disgusting” to Super Bowl Ads Being Dominated

You gain some, you lose some and sometimes you plateau

Together, these metabolic and vascular effects of GLP-1 serve to form the basis for the therapeutic potential of GLP-1 RAs in cardiovascular conditions

(20) Bone resorption marker CTX-1 remained unchanged in both groups, suggesting that the primary mechanism of liraglutides bone-preserving effects is enhanced bone formation rather than decreased resorption

Yet instead of CV risk, the strongest factors associated with the use of these novel diabetes medications were elevated HbA1c and younger patient age. Researchers collected data from 68,126 adults with type 2 diabetes hospitalized at one of seven hospitals in the province of Ontario in Canada from 2015 to 2020

More concerning but less common side effects include gallbladder problems , potential thyroid issues (a black box warning exists for medullary thyroid carcinoma risk in animal studies), and hair loss related to rapid weight loss rather than the medication itself