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Some patients achieve better tolerability by switching between injectable and oral formulations or between different GLP-1 compounds

Research Insight: Clinical trials have consistently shown that GLP-1 receptor agonists lead to significant delays in gastric emptying, contributing directly to reduced food intake and weight loss

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This article examines the evidence regarding Wegovy and nightmares, explores potential indirect factors affecting sleep during treatment, and provides guidance on managing sleep disturbances whilst using this medication

Specifically, GLP-1RAs exert protective effects on exercise-induced cardiomyopathy via increasing autophagy, reducing inflammation-related proteins and ROS generation via restoring the expression of catalase and manganese superoxide dismutase (MnSOD) [81]