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Due to their preclinical testing and lack of comparison with other dual receptor agonists such as tirzepatide, further studies are needed to determine whether the effects of these unimolecular compounds are superior to those of clinically tested drugs

GLP-1 receptor agonists (GLP-1-RA) were first developed for the treatment of type-2 diabetes, but have been recently approved for treatment of obesity

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However, as the effects do not persist over an entire 24 h period, its efficacy at lowering blood glucose levels and reducing body weight is lower than that of GLP-1 receptor agonists with a longer duration of action [3]

conceived the idea for the study