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Individuals with diabetes have an increased risk of developing neurodegenerative diseases, and the combination of cerebral and peripheral insulin resistance constitutes one of the main mechanisms underlying the initiation and progression of neurodegenerative diseases [23]

The unimolecular dual incretins were more successful than selective monoagonists and tackled the two basic causes of diabetes: pancreatic insulin insufficiency and obesity-induced insulin resistance

Coverage is far less ubiquitous for obesity and weight loss

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The first few weeks are primarily the body adapting to the appetite-regulating effects of the medication
