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Eating Patterns and Bowel Rhythm GLP-1 medications may reduce appetite, which can lead to skipped meals or decreased overall food intake

16,51 The anxiolytic effect of GLP-1 agonists has been hypothesized due to the preservation of brain-derived neurotrophic factor/nuclear factor erythroid 2related factor 2 levels, decreased oxidative stress, and lipocalin 2 levels in the hippocampus

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Off-label use is rarely covered by insurance, which can lead to high out-of-pocket costs, and has pushed some people toward compounded GLP-1 products, which are medications made by a pharmacy to create customized doses