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Results showed that patients who used a GLP-1 RA experienced greater reductions in disease activity and pain compared with controls

and Renal outcomes prevention: SGLT2 inhibitor plus a GLP-1 receptor agonist

The study showed that orforglipron led to significant weight changes in participants, especially at the highest dose
Slowed gastric emptying: One of the critical mechanisms of GLP-1 injections is their ability to slow down the emptying of the stomach

While the complete results of the study have not yet been published, an initial press release in 2024 indicated that tirzepatide reduced the relative risk for the composite endpoint (HF urgent visit or hospitalization, oral diuretic intensification, or cardiovascular death) by 38%
