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Appendix: What Is It, and What Does It Do

Metab Syndr Relat Disord (2015) 13(2):7883.10.1089/met.2014.0074 37 LamontBJLiYKwanEBrownTJGaisanoHDruckerDJ

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Neither mechanism directly stimulates insulin secretion in a glucose-independent manner, making the combination inherently safer regarding hypoglycaemia compared to sulphonylureas or insulin
Freezing can damage the peptide structure and create crystallization that makes the medication unreliable
