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Key Points Native human GLP-1 normalizes hyperglycaemia in patients with type 2 diabetes mellitus, but the short in vivo half-life of this hormone limits its therapeutic application A number of synthetic GLP-1 receptor agonists, with half-lives between 23 h and several days, have been developed for the long-term treatment of type 2 diabetes mellitus Short-acting GLP-1 receptor agonists (such as exenatide and lixisenatide) predominantly lower postprandial glucose levels and insulin concentrations via retardation of gastric emptying Long-acting GLP-1 receptor agonists (such as albiglutide, dulaglutide, exenatide long-acting release and liraglutide) predominantly lower blood glucose levels through stimulation of insulin secretion and reduction of glucagon levels Adverse effects of GLP-1 receptor agonists include nausea, vomiting and diarrhoea, injection-site reactions, antibody formation and increased heart rate This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

semaglutide education Weight Loss: How to Maximize Results See how semaglutide paired with

Jennifer Aniston, 56 Jens finished punishing her body

semaglutide education Weight Loss: How to Maximize Results See how semaglutide paired with

That made the FDAs 2021 approval of Novo Nordisks semaglutide (Wegovy) as an obesity treatment seem like something of a miracle

semaglutide education Weight Loss: How to Maximize Results See how semaglutide paired with

J., Hwang D., Song J., Kim M., Kyum Kim S., Kang K., Ahn J., Lee D., Kim M

semaglutide education Weight Loss: How to Maximize Results See how semaglutide paired with

The weight regain pattern is the important honest finding

semaglutide education Weight Loss: How to Maximize Results See how semaglutide paired with

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