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This approach may address prior limitations in efficacy and revive interest in the target

While BW reduction likely contributes to improvements in conditions, such as hepatic steatosis or sleep apnea, GLP-1 RAs may also exert direct disease-specific effects, particularly through central mechanisms implicated in neurodegeneration and addiction [39]

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Eligible Part D members pay $50 a month for a covered GLP-1 prescribed for weight management Claims and prior authorization go through a central processor, not the patient's regular Part D plan The $50 copay does not count toward the Part D deductible or annual out-of-pocket cap Patients already on a GLP-1 through Part D for diabetes, cardiovascular risk, sleep apnea, or MASH stay on their existing path Eligibility depends on BMI thresholds and conditions such as high blood pressure, heart failure, chronic kidney disease, prediabetes, or a history of cardiovascular disease

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