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Managing these symptoms effectively is crucial for maintaining well-being and medication compliance

Patients with personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, or acute pancreatitis should not use tirzepatide

Simplifying regimens through more effective single agents may improve outcomes through better compliance

A comprehensive comparison of the pharmacological and clinical characteristics of the major GLP-1RAs is provided in Table 3, encompassing parameters such as elimination, half-life, and adverse effect profiles

Drug-induced pancreatitis is characterized by inflammation of the pancreatic parenchyma and peripancreatic fat necrosis, often accompanied by sequelae such as severe abdominal pain, malabsorption, systemic inflammatory response syndrome (SIRS), organ failure, and, in severe cases, mortality [14]