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GLP1/E, at very low doses, is sufficient to ameliorate PCOS-associated metabolic alterations Since GLP1/E was superior to any other compound in terms of improvement of metabolic traits, we next assessed the metabolic efficacy of very low doses of this multi-agonist in our metabolically dysregulated PCOS model

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Some clinicians also explore microdosing tirzepatide for inflammation benefits rather than purely for weight loss, which involves even lower doses with less GI impact

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