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Retatrutide uniquely stimulates three critical metabolic receptors simultaneouslyGLP-1, GIP, and glucagonmaking it significantly more effective than peptides targeting a single receptor
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In these Ghsr+Glp1r+ neurons, ghrelin preadministration abolished the GLP-1-induced calcium response
A new finding after stopping GLP-1 drugs in a large cohort with Type 2 diabetes: rapid erosion of CV benefit/protection New @bmj_latest by @zalaly @Biostayan See thread:
The uncoupling of Mitochondria-ER Contact Sites (MERCS) represents a hallmark of metabolic dysfunction in obesity and type 2 diabetes
