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The mobile phases A and B contained 0.1% formic acid in distilled water and 0.1% formic acid in acetonitrile, respectively (Selen et al

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Furthermore, the mediation analysis should be interpreted with caution, as it assumes no confounding factors beyond those included in the model (baseline body weight and stratification factors), which may not be the case, given that postrandomization events (GI AEs) are used in the analysis

Mild burning that resolves within minutes to hours is generally considered a normal reaction, whereas persistent pain, spreading redness, or systemic symptoms warrant clinical evaluation

Semaglutide enhances glucose-dependent insulin secretion and suppresses inappropriate glucagon release, but these effects build gradually