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In one notable example, the company rejected a CAPA request related to burnt electrodes with air pockets, despite the nonconformance potentially causing "arcing and burning a patient." The rejection was justified because it was "the first-time instance of such an event," even though the issue carried significant patient risk

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Anecdotal evidence and smaller-scale studies have found patients taking GLP-1s for diabetes seem to have a lower risk of developing Alzheimers later on, but large-scale, long-term research is needed to confirm these findings