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Giving higher doses of tirzepatide (10 and 15 mg) lowers ALT, thus lower levels of procollagen III (pro-C3), which is a fibrosis marker in T2DM patients, and K-18 were seen [47]

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Current guidelines recommend that patients with diabetes receive an annual dilated eye exam, and a baseline exam is advisable before initiating GLP-1RA therapy in individuals with poor glycemic control or known retinopathy