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Recommended articles Optimising GLP-1RA Efficacy: A Meta-Analysis of Baseline Age and HbA1c as Predictors of MACE Reduction in T2DM Ghosal S, Ghosal A Diabetes, Metabolic Syndrome and Obesity 2025, 18:4347-4358 Published Date: 26 November 2025 Real-World Comparative Weight Loss of GLP-1 Receptor Agonists in the All of Us Research Program: A Retrospective Cohort Study Hwang I, Lee SW, Kim Y Drug Design, Development and Therapy 2026, 20:604247 Published Date: 14 July 2026

Week-by-Week Progress: Your First Month on GLP-1 Week 1: Adjusting to GLP-1 Treatment During the first week, your body starts adapting to the medication