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Treatment response should be evaluated through appropriate clinical follow-up rather than by whether nausea or other symptoms occur

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Keywords: Tirzepatide, GLP-1, Glucose-dependent insulinotropic peptide, Cardiovascular risk factors INTRODUCTION Tirzepatide is a synthetic peptide composed of 39 amino acids, which functions as a dual receptor agonist (RA) binding both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors and this unique mechanism of action resulted in the nickname twincretin. The structure of tirzepatide is based on that of the native GIP with the addition of a 20-carbon fatty diacid moiety, which increases its half-life to 5 days allowing for once-weekly administration

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And the medication could be mixed with other substances that could cause additional side effects. Having a conversation with a doctor can also help you learn more about the benefits and risks of taking a GLP-1 like semaglutide

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