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Description
In vitro investigations revealed its capacity to downregulate inflammatory gene expression and suppress the synthesis of interleukin 6 (IL-6), prostaglandin E2 and nitric oxide in chondrocytes and macrophages in a dose-dependent manner

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GLP-1 drugs Bariatric surgery remains the most effective option for long-term weight loss in appropriately selected patients

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- Oral semaglutide (only FDA approved for diabetes treatment) and injectable liraglutide, (FDA approved for obesity treatment as Saxenda,) lead to relatively modest amount of weight loss
