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In contrast, when analyzing stroke outcomes, the effect was more pronounced with GLP-1 RAs, which provided the greatest contribution to the reduction of stroke events
These hormones, which are mainly glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK), peptide YY (PYY), gastric inhibitory polypeptide (GIP) and ghrelin, influence the functioning of the digestive tract, but also modulate insulin secretion from the pancreas, the energy storage of adipose tissue and neuronal signalling in appetite centres in the brain to mediate the regulation of food intake by terminating hunger and inducing satiety

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