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The eGFR slope improved from a median of 2.37 mL/min/1.73 m 2 per year before treatment to +0.49 mL/min/1.73 m 2 per year during treatment, indicating significant renoprotective benefits [183]
doi: 10.1056/NEJMoa1612917 16 GreenJBHernandezAFDAgostinoRBGrangerCBJanmohamedSJonesNPet al
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The precision of this molecular targeting offers several distinct advantages for treating metabolic disorders: Selective Potency: It maximizes the production of cyclic AMP to drive glucose-dependent insulin release without overstimulating the system
