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Endogenous GLP-1 released from the gut acts directly on vagal afferents, which relay information from the abdomen to the brain and regulate multiple physiological systems

The American Heart Association (AHA) guidelines suggest the initiation of SGLT-2i or GLP-1RA in patients with T2DM who have additional cardiovascular risk factors [14]

In the add-on to sulfonylurea and add-on to insulin studies, hypoglycemia was also more commonly reported in patients treated with JANUVIA compared to placebo

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Choosing a GLP-1 Clinic in Denver GLP-1 medications should be prescribed and monitored by a qualified provider