contraindications for glp-1 agonists include Table 5 from Glucagon-Like Peptide-1 (GLP-1) Receptor Drug Class Review GLP-1RA Essentials in Gastroenterology: Side

This is simply because Ozempic drug trials focused on how it impacted blood sugar (like metformin does), while Wegovy drug trials focused on how it impacted weight

For example, in 2023 analysts at the investment bank Jeffries estimated that 'if the average United Airlines passenger were to lose 10lbs (4.5kg), it would save the airline $80m a year in fuel costs (Economist)

Zhang L-Y, Jin Q-Q, Hlscher C, et al

The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets

Some of these drugs are now also approved to reduce the risk of heart attacks , strokes, and heart-related deaths in certain populations