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Combination therapy reduced glycated haemoglobin (HbA1c) by a mean of 0.44% more than other therapies and significantly improved the likelihood of achieving an HbA1c of 7.0% or lower, with a relative risk (RR) of 1.92

A total of 3,183 participants of 50 years of age with established CVD or CKD, or 60 years of age with CV risk factors were only observed for a median of 15.9 months

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Injectable therapies may offer better adherence due to less frequent dosing

Some patients may experience mild dehydration secondary to the gastrointestinal side effects commonly associated with Rybelsus, particularly nausea, vomiting, and diarrhoea