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And it asks a simple question: Who do we trust when science, marketing, access, and manufacturing all collide at once

Hence, it is best to develop proper eating habits and exercise programs while on the medication to help with maintenance after the medication has been discontinued

To account for the pronounced heterogeneity of the preclinical evidence base, specific inclusion criteria for preclinical studies were defined as follows: (1) Model Type: utilization of established in vivo models (e.g., transgenic AD models like APP/PS1 or 3xTg-AD, neurotoxin-induced PD models, middle cerebral artery occlusion for ischemia, or high-fat diet for metabolic dysfunction) or relevant in vitro neuronal/glial cell lines