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2024, Garvey WT, Batterham RL, Bhatta M, et al

Consequently, we infer that racial disparities in the efficacy of oral semaglutide for weight reduction (the minimum effective dose was lower in non-Asian patients) are more likely attributable to variations in the expression of neurons within the central nervous system, rather than differences in systemic GLP-1 metabolism

Since insulin resistance plays a crucial role in several reproductive disorders, particularly polycystic ovary syndrome (PCOS), the metabolic improvements induced by GLP-1 agonists may have beneficial effects on reproductive function

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