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GLP-1 receptor agonists (semaglutide, liraglutide, tirzepatide) do not have formal alcohol contraindications in their UK product information Alcohol may exacerbate common side effects including nausea, vomiting, and abdominal discomfort, particularly during initial treatment or dose escalation Hypoglycaemia risk increases significantly when combining alcohol with insulin or sulfonylureas alongside weight loss injections UK Chief Medical Officers recommend no more than 14 units weekly, spread over three or more days with alcohol-free days Complete alcohol avoidance is advised for patients with pancreatitis history, severe liver disease, or problematic alcohol use Always discuss alcohol consumption with your prescribing clinician to receive personalised guidance appropriate to your circumstances Table of Contents Can You Drink Alcohol While on Weight Loss Injections