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However, this inhibitory effect is significantly weakened in patients with T2DM, indicating that its potential application in diabetes treatment requires further investigation
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exenatide, lixisenatide) were designed to resist DPP-4 metabolism, and had half-lives of ~3hrs necessitating twice-daily or daily dosing
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In the GLP-1 RA group, 33 participants were subsequently newly diagnosed with heart failure, compared with 15 in the SGLT2i group (RR 0.44 [95% CI 0.23, 0.83] p =0.0092)
