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For type 2 diabetes, GLP-1 receptor agonists are typically considered when metformin and other oral glucose-lowering medications have not achieved adequate glycaemic control, or when certain clinical circumstances make them particularly appropriate

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Many studies have shown a U- or J-shaped relationship between BMI and mortality, where lower and higher BMI are associated with increased mortality risk compared to normal weight BMI levels (defined as a BMI between 18.5 to 25 kg/m)

GLP-1 receptors are expressed in brain regions associated with emotional regulation, including the hippocampus, amygdala, and prefrontal cortex

Around 38% of women with PCOS experience poor absorption, a limitation that some supplements address with ingredients like alpha-lactalbumin