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Like GLP-1, OXM is rapidly degraded in the circulation by DPP-IV

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Furthermore, in 3T3-Ll adipocytes, GLP-1 stimulation improved insulin responsiveness by promoting increased glucose uptake and FA synthesis in adipose cells [80], possibly by CREB phosphorylation and ERK1/2 activation [81]

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To form an active G protein-coupled complex, HA-GLP-2R(1490)-LgBiT-TEV-OMBP-MBP was co-expressed with a dominant-negative bovine G s (DNG s ), rat G1-HiBiT and bovine G2 in Sf 9 insect cells

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