is metformin a glp-1 drug New aspects of an old drug: as glucagon-like peptide 1 (GLP-1) enhancer and sensitiser | Diabetologia Do You Still Need Metformin
Description
These agents are recommended as first-line therapy by the American Diabetes Association and the European Society of Cardiology for patients with diabetes and underlying cardiovascular disease [4, 5]

Moreover, in another face to face 26-week study, dulaglutide 1.5 or 0.75 mg significantly increased heart rate compared with exenatide 10 g BID (2.8 vs

[4] [5] The lipid improvements with GLP-1 therapy are generally proportional to the degree of weight loss achieved, and individual responses vary considerably

They are made by different companies (Innovent Biologics and Eli Lilly, respectively), have different clinical trial programs, and produce different levels of weight loss

Clinical Medicine
