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Josh Morgan / USA TODAY NETWORKDETROIT, July 24, 2024 ~ Popular prescription drugs Ozempic and Wegovy, both of...

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No, but semaglutide did improve a persistence/effort in a this secondary analysis: Although it failed to improve mood or cognition in this original study (randomized, major depression with overweight/obesity)

Moreover, the activation of M1 microglia was also inhibited by semaglutide, which may be related to its protective effects

Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity