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Bariatric surgery works fantastic because it permanently alters the signaling system

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A February 2026 peer-reviewed study (Kasher Meron et al.) found an 11% higher fragility fracture risk in GLP-1 users aged 65+ with Type 2 diabetes versus those on other diabetes medications - a retrospective study showing association, not proven causation

Side effects Common gastrointestinal side effects of GLP-1 medications are nausea, vomiting, diarrhea, constipation, abdominal discomfort, and stomachache

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