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Given that GLP-1RAs are demonstrating efficacy in diseases beyond weight loss and diabetes, their use is only going to increase
A 2025 meta-analysis published in PMC pooling data from over 140,000 participants found that tirzepatide produced an average of 4.23 percentage points more weight loss than semaglutide across both clinical trials and real-world settings (source)
Journal of the American College of Nutrition , 28(6), 723732
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Thermo Fisher Scientific, USA), respectively
