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Structure and function studies of glucagon-like peptide-1 (GLP-1): the designing of a novel pharmacological agent for the treatment of diabetes

Retatrutide's phase 2 obesity data (around 24% at the top dose) edged tirzepatide's SURMOUNT-1 result (about 21%), but they come from different trials, not a head-to-head, and retatrutide is not approved
But tolerability is deeply individual

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Patients should be careful that they are translating the units correctly as some people have injected themselves with too high concentrations of the drug
