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Second, consider whether the nausea timing suggests one medication is primarily responsible, such as nausea that worsens after taking your morning bupropion versus nausea that peaks 24 to 48 hours after your tirzepatide injection

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AUTHOR CONTRIBUTIONS All the authors participated in the interpretation of the data and critical review of the manuscript and approved this manuscript to be submitted for publication

However, body weight does influence the practical experience of dosing in meaningful ways

Doserelated increase in heart rate of 0.6-2.6 beats per minute (bpm) was reported with tirzepatide versus 0.1 bpm in the placebo group [6]