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doi: 10.1016/j.brainres.2007.01.107 143 LeibelRLChungWKChuaSC

Notably, recent findings have described the pleiotropic effects of SGLT-2is in terms of cardioprotection as well as renoprotection (1319)

ER Unfolded Protein Response A cellular condition on which metabolically mediated and inflammation-driven pathologies converge is ER stress and the associated UPR

Up to 24.2% body weight reduction over 48 weeks

10.1016/j.tips.2007.06.003 33 KushnerR
