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Obesity Disease Burden and Population Health ROI Framework Economic Cost of Obesity, Comorbidity Cascade, and GLP-1 Pharmacotherapy Value-Based Evidence Reshape Global Treatment Investment The Global Obesity Forum estimated total annual economic costs of obesity at USD 4.32 trillion annually in 2025 , representing 2.92% of global GDP and exceeding the full economic output of Germany

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The American Diabetes Association (ADA) recommends that patients spend at least 70% of their CGM readings within the target range of 70180 mg/dL (3.910.0 mmol/L), with less than 4% of readings below 70 mg/dL (time below range, TBR) [39]

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