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TSA confirmed that enough patients were randomized and again no association of the medications and pancreatic cancer was observed considering a NNH of 1000 and the short mean follow-up of the included trials (1.7 years)

However, Mounjaro is sometimes used off-label for weight loss, and Zepbound may be used off-label for managing blood sugar

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Are there any anticipated studies focusing on the real-world effectiveness and safety of these generics compared to the branded product in these specific high-burden regions

2 Similarly, in the SURMOUNT-1 study, participants received individualized lifestyle counseling with goals of achieving a 500 kcalday 1 energy deficit and increasing physical activity to 150 minweek 1 physical activity