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Description
GLP-1 acts on insulin secretion and satiety: it increases insulin and decreases glucagon secretion, thereby blocking the endogenous production of glucose and decreasing glycemia after a meal

W., Wu, C

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Adipose tissue in obese individuals secretes adipokines (e.g., leptin, lipocalin, resistin) and inflammatory factors (e.g., TNF-, IL-1, IL-6), impacting KOA progression ( The existing studies suggest that GLP-1 RAs protect against KOA through anti-inflammatory, anti-apoptotic, autophagy regulation, macrophage polarization mechanisms, etc

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