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In prostate cancer, GLP1R is highly expressed in metastatic CRPC, with preclinical data indicating that short-acting agonism with the GLP1R agonist exenatide directly affects signaling in prostate cancer models to decrease proliferation (23-25)

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Liraglutide is a once-daily GLP-1 injection used for weight management in individuals with overweight or obesity , including some adolescents

The reduction in right ventricular end-diastolic area (RVEDA) and the improvements in right ventricular fractional area change (RVFAC) and tricuspid annular plane systolic excursion (TAPSE) suggest that semaglutide not only attenuates RV dilation but also enhances the contractile function of the RV