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Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

However, losing this much weight remains a challenge for most patients, especially with lifestyle modifications alone

Ozempic received FDA approval for type 2 diabetes, not weight loss, yet doctors prescribe it off-label for weight management

He received the award, together with Daniel Joshua Drucker, Joel Habener, Svetlana Mojsov, for their discovery and characterisation of the biologically active form of the hormone glucacon-like peptide (GLP-1)

Yes Data for this study were extracted from the published literature