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Horn, D.B

Covering GLP-1s for diabetes but not weight loss is increasingly common among health plans across the country due to rising costs on the healthcare system

Weight loss is a frequent symptom of PD progression, which can be severe with rapid changes in body weight [96]

Importantly, dual and triple GLP-1R/Gastric inhibitory polypeptide receptor (GIP-R) agonists have been developed, maximizing the beneficial effects and minimizing the adverse effects of these agents

Other classes of obesity medications, including the centrally acting medications phentermine-topiramate, naltrexone-bupropion, phentermine (available since the 1960s) and the gastrointestinal lipase inhibitor orlistat are associated with a weight reduction of 510 % of mean body weight [28]