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Synthesis and biological evaluation of triazole based uracil derivatives as novel DPP-4 inhibitors

These medications work by mimicking the action of GLP-1, thereby helping to regulate blood sugar levels and reduce appetite

Historically, they have been described as incretin hormones because of their effect on postprandial insulin release, but they exert effects on multiple organs beyond the pancreatic islet

It feeds beneficial bacteria in the gut and helps increase the production of short-chain fatty acids

Researchers who sail through the week 24 period without concerning heart rate changes can generally be reassured that their cardiovascular response is within acceptable parameters for continued use