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Weight fluctuationswhether loss or gainare well-recognised factors that can alter the hypothalamic-pituitary-ovarian axis, which governs the menstrual cycle

Notably, GLP-1 and irisin are synthesized within the pancreatic islets in - and -cells, respectively, and share comparable pleiotropic effects, activating similar intracellular pathways [93]

Group comparisons were performed using the MannWhitney U test for continuous variables and the chi-square test for categorical variables

Riesgo Cardiovascular: Si tienes antecedentes de enfermedad cardiovascular o factores de riesgo como hipertensin arterial o niveles elevados de colesterol