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Systemic chronic inflammation caused by hyperglycemia leads to injury of both brain vessels and surrounding tissues

Tirzepatide in addition to being a GLP-1 receptor agonist like Semaglutide, it also is a GIP receptor agonist and increases energy expenditure resulting in weight loss

It depends on an individuals unique health, medical history, and specific circumstances

By the end of week two, the appetite-suppressing effect typically becomes pronounced enough that portion sizes naturally decrease without conscious effort

It is a reason to escalate more slowly, to take GI management seriously from day one, and to understand that a rough week does not mean the drug is not working or is not right for you