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As of this review, only one large randomized clinical trial of semaglutide in youth has been completed, with a follow-up duration of 68 weeks [54]

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Uncommon: Constipation, skin reactions, arthralgia, hypoglycaemia, peripheral oedema

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Notably, recent findings have described the pleiotropic effects of SGLT-2is in terms of cardioprotection as well as renoprotection (1319)

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