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Glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists reduce body weight, glycaemia, blood pressure, postprandial lipaemia and inflammation actions that could contribute to the reduction of cardiovascular events

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5 GLP-1RAs in obesity treatment 5.1 Weight loss efficacy GLP-1 receptor agonists exhibit significant weight loss via many molecular routes

Four participants did not complete the trial: two because of their desire to use semaglutide after the first intervention rather than continue the study, one because of difficulty complying with the study procedures and one because of the side effects of 0.5 mg semaglutide (Fig